John Bell

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Senior Scientist, Cancer Therapeutics Program, Ottawa Hospital Research Institute

Professor, Depts. of Medicine and Biochemistry, Microbiology & Immunology, University of Ottawa

Program Director, Ontario Regional Biotherapeutics Program(ORBiT), Ontario Institute for Cancer Research, OICR

Director, Canadian Oncolytic Virus Consortium (COVCo), Terry Fox New Frontiers Program Project Grant

Scientific Director, BioCanRx, Biotherapeutics for Cancer Treatment, Network of Centres of Excellence (NCE)

 

Full Biography

 

Research Interests and Clinical Approach

Our research program is directed towards the identification and characterization of novel cancer killing therapeutic viruses that selectively infect and kill cancer cells, while leaving healthy cells and tissues unharmed. Not only do we discover and design new therapeutic viruses, but we also manufacture them for eventual clinical translation and commercialization.

 

Projects at BioCanRx

Development of a Virally Programmed Exosome-based Cancer Vaccine Platform

 

A Phase 1/1b, Multicenter, Open-label Trial of Oncolytic MG1 Expressing Mutant Human Papilloma Virus (HPV) E6 and E7 (MG1-E6E7), with Adenovirus Vaccine Expressing Mutant HPV E6 and E7 (Ad-E6E7) and Atezolizumab in Patients with HPV Associated Cancers

 

Development of a Novel, Phase 1-Ready, Viro-Immunotherapeutic

 

CREATING T-CELL RECEPTORS THAT REACT TO SPECIFIC TUMOUR ANTIGENS FOR IMPROVED ADOPTIVE T-CELL THERAPY

 

COMBINING ONCOLYTIC VACCINE THERAPY WITH ADOPTIVE CELL THERAPY TO TARGET CANCERS EXPRESSING MAGE-A3

 

Recent Articles

Researchers join the fight against COVID-19

 

Dr. John Bell Featured on Science Podcast

 

John Bell Wins Inaugural ESGCT Public and Patient Engagement Award

 

World Cancer Day 2019: A Message from Dr. John Bell, Scientific Director and Dr. Stéphanie Michaud, President & CEO BioCanRx

 

Dr. John Bell Receives Canadian Cancer Research Alliance Award

 

Dr. John Bell receives award for Outstanding Achievements in Cancer Research

 

Dr. John Bell speaks to CBC News about the FDA approval of a second CAR-T cell therapy

 

Dr. John Bell speaks to CBC News on how BioCanRx researchers are working out a made-in-Canada CAR-T cell therapy protocol

 

New buzz about immunotherapy – A Canadian perspective with Dr. John Bell

 

Together, we can! A message from Dr. John Bell on World Cancer Day