Clinical, Social and Economic Impact Projects

Excelerating tumor-infiltrating lymphocytes (TIL) as a treatment for melanoma (TIL-ME)

 

Dean Fergusson & Manoj Lalu, Ottawa Hospital Research Institute
Approved October 2024 | $215,594 from BioCanRx

 

Eligible cancers: Melanoma

 

Keywords: Tumor, Immunotherapy, Lymphocytes, Melanoma, Excelerator, Systematic reviw, Clinical trial protocol, Economic analysis

 
 

 
 

Making Patient Partnerships A Reality in Very Early Phase Clinical Trials (MARVEL): Development of a Patient Engagement Platform

 

Dr. Manoj Lalu, Ottawa Hospital Research Institute
Approved October 1, 2020 | Project value $583,950 | 4 partner | $361,490 from BioCanRx

 

 
 

 
 

Identifying Effect Modifiers of CAR T-Cell Therapeutic Efficacy

 

Dr. Dean Fergusson, Ottawa Hospital Research Institute
Approved July 1, 2020 | Project value $190,000 | 5 partner | $100,000 from BioCanRx

 

 
 

 
 

Assessing the Real-World Clinical and Economic Outcomes of Emerging Innovative Technologies in Oncology: The Cases of Biosimilars and CAR T-cells

 

Dr. Kelvin Chan, Sunnybrook Research Institute
Approved April 1, 2019 | Project value $297,217 | 3 partner | $100,000 from BioCanRx

 

 
 

 
 

Using real-world data and iterative economic evaluation to prioritize resource allocation for care and research in adult patients with relapsed/refractory B-cell acute lymphoblastic leukemia

 

Dr. Kednapa Thavorn, Ottawa Hospital Research Institute
Approved April 1, 2019 | Project value $284,955 | 4 partner | $100,000 from BioCanRx

 

 
 

 
 

Developing System-level Policy Model for regenerative medicine and cell therapy in Oncology

 

Dr. William WL Wong, University of Waterloo School of Pharmacy
Approved April 23, 2018 | Project value $100,000 | 1 partner | $100,000 from BioCanRx

 

 
 

 
 

Getting better Outcomes with Chimeric Antigen Receptor T-cell therapy (GO–CART): A BioCanRx Research Excelerator to Safely and Effectively Translate CAR-T Cell Therapy for Hematological Malignancies

 

Dr. Manoj Lalu, The Ottawa Hospital Research Institute, University of Ottawa
Approved January 17, 2016 | Project value $414,441 | 6 partners | $364,441 from BioCanRx

 

 
 

 
 

Translational Cancer Immunotherapeutics: Improving the Design, Analysis, and Reporting of Preclinical Studies

 

Dr. Dean Fergusson, The Ottawa Hospital Research Institute, University of Ottawa
Approved January 17, 2016 | Project value $196,093

 

 
 

 
 

TOWARDS RATIONAL DESIGN OF POLICIES AND PRACTICES TO ENABLE CLINICAL TRANSLATION OF NOVEL CANCER BIOTHERAPEUTICS IN CANADA

 

Dr. Tania Bubela, Simon Fraser University
Approved January 5, 2016 | Project value $346,386 | 7 partners | $346,386 from BioCanRx

 

 
 

 
 

IMPROVING THE QUALITY OF JUDGEMENT IN CANCER THERAPEUTICS DEVELOPMENT

 

Dr. Jonathan Kimmelman, McGill University
Approved January 5, 2016 | Project value $534,846 | 1 partner | $534,846 from BioCanRx