Tag: Basic research

Karen Mossman

Professor, Pathology and Molecular Medicine, McMaster University Vice President, Research, McMaster University   Full Biography   Cancers of Interest Breast Cancer   Projects at BioCanRx In vivo genome-wide CRISPR/Cas9 screen to identify genes that limit curative checkpoint blockade immunotherapy in triple negative breast cancer   Recent Articles I study viruses: How our team isolated the… Read more »

Jason Moffat

Professor & Principal Investigator, Department of Molecular Genetics, University of Toronto Canada Research Chair in Functional Genomics of Cancer   Full Biography   Cancers of Interest Skin   Research and clinical approaches Our research is concentrated in three areas:   Identification of genetic interactions and differential gene essentiality in mammalian cancer cell lines Cancer cell… Read more »

Julian Lum

Senior Scientist, BC Cancer Associate Professor, Biochemistry, Microbiology and Biology, University of Victoria   Full Biography   Cancers of Interest Prostate Ovarian   Research and Clinical Approaches Metabolomics Raman Spectroscopy Flow Cytometry Immunoassays T cells Immunohistochemistry Radioligand targeted therapy   Projects at BioCanRx Targeted RadioLigand (tRL) and checkpoint blockade for metastatic castrate resistant prostate cancer… Read more »

Brian Lichty

PhD, Associate Professor, Pathology and Molecular Medicine, McMaster   Full Biography   Cancers of Interest Breast Cervical Gynecological Lung Prostate Skin   Projects at BioCanRx Development of a Virally Programmed Exosome-based Cancer Vaccine Platform   COMBINING ONCOLYTIC VACCINE THERAPY WITH ADOPTIVE CELL THERAPY TO TARGET CANCERS EXPRESSING MAGE-A3   A Phase 1/1b, Multicenter, Open-label Trial… Read more »

Megan Levings

Investigator, BC Children’s Hospital (Lead, Childhood Diseases Research Theme) Professor, Department of Surgery, Faculty of Medicine, University of British Columbia   Full Biography   Cancers of Interest Blood   Research Interests and Clinical Approach Cell Therapy Transplantation   (https://www.bcchr.ca/levingslab)   Projects at BioCanRx Garbage to Gold: expansion of Therapeutic Regulatory T Cells from discarded thymus… Read more »

Aly-Khan Lalani

Assistant Professor, Oncology, McMaster University   Full Biography   Cancers of Interest Bladder Gastrointestinal Stromal Tumours (GIST) Genitourinary Kidney Prostate Soft Tissue Sarcoma Testicular   Projects at BioCanRx   Phase II CYTOSHRINK Trial: Cytoreductive Stereotactic Hypofractionated Radiotherapy with Combination Ipilimumab and Nivolumab for Metastatic Kidney Cancer

James Koropatnick

Distinguished Oncology Scientist of the London Regional Cancer Program (London Health Sciences Centre) Director, Strategic Training Program in Cancer Research and Technology Transfer Assist. Director, Lawson Health Research Institute   Full Biography   Cancers of Interest Breast Colorectal Gastrointestinal Stromal Tumours (GIST) Head and Neck Lung Neuroblastoma Pancreatic   Projects at BioCanRx Advanced preclinical development… Read more »

Natasha Kekre

Associate Scientist, Clinical Epidemiology Program, Ottawa Hospital Research Institute Hematologist, Blood and Marrow Transplant Program, The Ottawa Hospital Associate Professor, University of Ottawa   Full Biography   Cancers of Interest Blood   Research Interests Hematopoietic Stem Cell Transplantation Oncolytic Viruses Cellular immunotherapy (CAR-T cells) Leukemia Lymphoma Clinical Epidemiology   Projects at BioCanRx Clinical Trial Enabling… Read more »

Carolina Ilkow

Senior Scientist, Cancer Therapeutics Program, Ottawa Hospital Research Institute Associate Professor, University of Ottawa   Full Biography   Cancers of Interest Breast Cervical Colorectal Gynecologic Head and Neck Ovarian Pancreatic   Projects at BioCanRx Development of a Virally Programmed Exosome-based Cancer Vaccine Platform

Naoto Hirano

Senior Scientist, Princess Margaret Cancer Centre   Full Biography   Cancers of Interest Blood, Breast, Lung, Ovarian, Pancreatic, Prostate, Skin, Soft Tissue Sarcoma   Research Interests and Clinical Approach Dr. Hirano’s research team is particularly interested in understanding how the interactions between T cells and antigen-presenting cells affect priming, expansion, persistence and differentiation of T… Read more »