Investigator, BC Children’s Hospital
Lead, Childhood Diseases Research Theme
Cancers of Interest
Research Interests and Clinical Approach
“My research focuses on immune cells called T regulatory cells (Tregs) that are central to immune tolerance and that are a very promising new therapeutic tool. To exploit the natural capacity of Tregs to induce immune tolerance, and to design effective therapies to restore immune tolerance in patients with immune-mediated disease, we need to define how, when and where Tregs function in the body.
My research program has 3 major themes that aim to (i) build on our recent discoveries to understand Treg biology and (ii) apply that knowledge to develop and assess treatments designed to manipulate immune tolerance. My work integrates lab and clinical studies, applies advanced methods in the context of transplant rejection and autoimmunity, and creates outputs with broad relevance for chronic immune-mediated diseases.”